Plasma Separation: Choosing the Right Tubes for Blood Sample Collection
Summary
- Lithium Heparin tubes are commonly used in clinical labs for blood sample collection.
- These tubes are not ideal for plasma separation as they may interfere with Test Results.
- It is recommended to use EDTA tubes for plasma separation in a medical laboratory setting.
Introduction
When it comes to collecting blood samples for laboratory testing, the type of tube used can make a significant difference in the accuracy of the results. In a medical laboratory setting, plasma separation is a crucial step in many tests, and it is important to use the correct tubes to ensure the integrity of the samples. One question that often arises is whether lithium Heparin tubes can be used for collecting blood samples for plasma separation. In this article, we will explore this topic in the context of home healthcare, clinical labs, and hospitals in the United States.
What are Lithium Heparin Tubes?
Lithium Heparin tubes are commonly used in clinical labs for blood sample collection. Heparin is a substance that prevents blood clotting by inhibiting the activity of thrombin, an enzyme that is responsible for the formation of blood clots. Lithium Heparin tubes contain lithium salt, which enhances the Anticoagulant properties of Heparin. These tubes are typically used for collecting whole blood samples for a variety of tests, including chemistry panels, blood gases, and electrolyte tests.
Can Lithium Heparin Tubes be Used for Plasma Separation?
While lithium Heparin tubes are excellent for collecting whole blood samples, they are not ideal for plasma separation. When blood is collected into a lithium Heparin tube, the Heparin prevents clotting by inhibiting the activity of thrombin. However, if the sample is centrifuged to separate the plasma from the red blood cells, the Heparin can interfere with some tests. This is because Heparin can bind to certain proteins in the plasma, which may affect the accuracy of the Test Results.
Recommendations for Plasma Separation
For plasma separation in a medical laboratory setting, it is recommended to use tubes that contain different anticoagulants, such as EDTA (ethylenediaminetetraacetic acid). EDTA is a chelating agent that binds calcium ions, which are necessary for blood clotting. Unlike Heparin, EDTA does not interfere with most tests and is therefore a better choice for plasma separation. EDTA tubes are commonly used for tests that require plasma, such as CBC (complete blood count), coagulation studies, and blood cultures.
Conclusion
In conclusion, while lithium Heparin tubes are excellent for collecting whole blood samples in a clinical lab setting, they are not recommended for plasma separation. When it comes to separating plasma from whole blood, it is best to use tubes that contain EDTA as the anticoagulant. By using the appropriate tubes for plasma separation, Healthcare Providers can ensure the accuracy and reliability of laboratory Test Results.
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